The overarching goal of the Woo Center for Big Data and Precision Health is to improve health care on a global scale by harnessing the power of big data, machine learning, and precision medicine. Today, biomedical imaging and sensing technologies are gathering real-time health data at an unprecedented pace. Powerful computers can probe the complexity of entire genomes, and electronic recordkeeping offers new opportunities to analyze population-level disease patterns and issues in clinical care delivery. The emergence of novel precision medicine strategies has empowered us with robust tools to guide treatments for patients. At the Woo Center, we have formed an interdisciplinary team with strong research interests in these three areas: 1) AI imaging; 2) health data; and, 3) precision medicine.